Baclofen (baclofen): Reviews and patient testimonials

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Medication indications

Baclofen 0.05mg/ml solution for injection

Baclofen Aguettant is indicated in patients with severe chronic spasticity resulting from trauma, multiple sclerosis or other spinal cord disorders, who are unresponsive to oral baclofen or other orally administered antispastic agents and/or those patients who experience unacceptable side effects at effective oral doses.

Baclofen Aguettant is effective in adult patients with severe chronic spasticity of cerebral origin, resulting e.g. from cerebral palsy, brain trauma or cerebrovascular accident; however, clinical experience is limited.

Paediatric population

Baclofen Aguettant is indicated in patients aged 4 to <18 years with severe chronic spasticity of cerebral origin or of spinal origin (associated with injury, multiple sclerosis, or other spinal cord diseases) who are unresponsive to orally administered antispastics (including oral baclofen) and/or who experience unacceptable side effects at effective oral doses.

Baclofen 0.5mg/ml solution for infusion

Baclofen Aguettant is indicated in patients with severe chronic spasticity resulting from trauma, multiple sclerosis or other spinal cord disorders, who are unresponsive to oral baclofen or other orally administered antispastic agents and/or those patients who experience unacceptable side effects at effective oral doses.

Baclofen Aguettant is effective in adult patients with severe chronic spasticity of cerebral origin, resulting e.g. from cerebral palsy, brain trauma or cerebrovascular accident; however, clinical experience is limited.

Paediatric population

Baclofen Aguettant is indicated in patients aged 4 to <18 years with severe chronic spasticity of cerebral origin or of spinal origin (associated with injury, multiple sclerosis, or other spinal cord diseases) who are unresponsive to orally administered antispastics (including oral baclofen) and/or who experience unacceptable side effects at effective oral doses.

Baclofen 2mg/ml Solution for Infusion

Baclofen Aguettant is indicated in patients with severe chronic spasticity resulting from trauma, multiple sclerosis or other spinal cord disorders, who are unresponsive to oral baclofen or other orally administered antispastic agents and/or those patients who experience unacceptable side effects at effective oral doses.

Baclofen Aguettant is effective in adult patients with severe chronic spasticity of cerebral origin, resulting e.g. from cerebral palsy, brain trauma or cerebrovascular accident; however, clinical experience is limited.

Paediatric population

Baclofen Aguettant is indicated in patients aged 4 to <18 years with severe chronic spasticity of cerebral origin or of spinal origin (associated with injury, multiple sclerosis, or other spinal cord diseases) who are unresponsive to orally administered antispastics (including oral baclofen) and/or who experience unacceptable side effects at effective oral doses.

Baclofen 5mg/5ml Oral Liquid

Baclofen oral liquid is indicated for the relief of spasticity of voluntary muscle resulting from such disorders as: multiple sclerosis, other spinal lesions, e.g. tumours of the spinal cord, syringomyelia, motor neurone disease, transverse myelitis, traumatic partial section of the cord.

Baclofen oral liquid is also indicated in adults and children for the relief of spasticity of voluntary muscle arising from e.g. cerebrovascular accidents, cerebral palsy, meningitis, traumatic head injury.

Patient selection is important when initiating baclofen therapy; it is likely to be of most benefit in patients whose spasticity constitutes a handicap to activities and/or physiotherapy. Treatment should not be commenced until the spastic state has become stabilised.

Paediatric population:

Baclofen is indicated in patients 0 to <18 years for the symptomatic treatment of spasticity of cerebral origin, especially where due to infantile cerebral palsy, as well as following cerebrovascular accidents or in the presence of neoplastic or degenerative brain disease.

Baclofen is also indicated for the symptomatic treatment of muscle spasms occurring in spinal cord diseases of infectious, degenerative, traumatic, neoplastic, or unknown origin such as multiple sclerosis, spastic spinal paralysis, amyotrophic lateral sclerosis, syringomyelia, transverse myelitis, traumatic paraplegia or paraparesis, and compression of the spinal cord.

Baclofen Tablets 10mg

Baclofen is indicated for the relief of spasticity of voluntary muscle resulting from such disorders as multiple sclerosis, other spinal lesions e.g. tumours of the spinal cord, syringomyelia, motor neurone disease, transverse myelitis, traumatic partial section of the cord.

Baclofen is also indicated in adults and children for the relief of spasticity of voluntary muscle arising from e.g. cerebrovascular accidents, cerebral palsy, meningitis, traumatic head injury.

Patient selection is important when initiating baclofen therapy; it is likely to be of most benefit in patients whose spasticity constitutes a handicap to activities and/or physiotherapy. Treatment should not be commenced until the spastic state has become stabilized.

Paediatric population

Baclofen is indicated in patients 0 to <18 years for the symptomatic treatment of spasticity of cerebral origin, especially where due to infantile cerebral palsy, as well as following cerebrovascular accidents or in the presence of neoplastic or degenerative brain disease.

Baclofen is also indicated for the symptomatic treatment of muscle spasms occurring in spinal cord diseases of infectious, degenerative, traumatic, neoplastic, or unknown origin such as multiple sclerosis, spastic spinal paralysis, amyotrophic lateral sclerosis, syringomyelia, transverse myelitis, traumatic paraplegia or paraparesis, and compression of the spinal cord.

Baclofen Tablets BP 10mg

Baclofen is indicated for:

1) The relief of spasticity of voluntary muscle resulting from disorders such as multiple sclerosis and other spinal lesions, including tumours of the spinal cord, motor neurone disease, syringomyelia, transverse myelitis and traumatic partial section of the spinal cord.

2) Adults and children in the relief of spasticity of voluntary muscle arising from conditions such as cerebral palsy, cerebrovascular accidents, traumatic head injury and meningitis.

Treatment with Baclofen should not be initiated until the spastic state has become stabilised and it should be administered selectively; it is most likely to be of benefit to patients whose spasticity constitutes a handicap to activities or physiotherapy.

Paediatric population

Baclofen is indicated in patients 0 to <18 years for the symptomatic treatment of spasticity of cerebral origin, especially where due to infantile cerebral palsy, as well as following cerebrovascular accidents or in the presence of neoplastic or degenerative brain disease.

Baclofen is also indicated for the symptomatic treatment of muscle spasms occurring in spinal cord diseases of infectious, degenerative, traumatic, neoplastic, or unknown origin such as multiple sclerosis, spastic spinal paralysis, amyotrophic lateral sclerosis, syringomyelia, transverse myelitis, traumatic paraplegia or paraparesis, and compression of the spinal cord.


Route of administration: Injectable, Oral
Molecule: baclofen

Patients' opinions on Baclofen

In brief

General satisfaction level: 6.83/10 Learn more

Treatment's effectiveness: 6.33/10 Learn more

Ease of use: 7.67/10 Learn more

Adherence to prescription: 7.50/10 Learn more

Detected side effects: 2.80/10 Learn more

Improvement in the quality of life: 6.83/10 Learn more

1 = Not at all satisfied
10 = Extremely satisfied

1 = Not at all satisfied
10 = Extremely satisfied

1 = Not at all satisfied
10 = Extremely satisfied

1 = Never
10 = Always

1 = Not at all important
10 = Extremely important

1 = Not at all satisfied
10 = Extremely satisfied

Tips and advice of the community


avatar
Yank34
on 03/07/2020

1) Endeavouring to live my life as fully as possible BUT also needing to be more mindful re: "over-doing" activities because these inevitably result in extremely limited functioning (on every level) the next day or 2!

2) Embarked on a NHS online CBT (Cognitive Behavioural Therapy) program (Silvercloud) about the same time as "lockdown" due to experiencing increasing anxiety/depressive symptoms after my husband dying in March 2019.  This training has been very effective in changing my perspective(s) to living after simultaneously experiencing so, so many traumatic events before and after my husband passed away.  May be worth a try for others?

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avatar
Luckie1
on 03/03/2020

Hi there I've had ms ( officially diagnosed since 2910) although think I've had it longer. I took baclofen for quite a long time 10mg twice a day but found that I had bladder problems i.e. Couldn't control the urge that go to the toilet do ended up weeding myself quite alot( as I had no control) I now take half a tablet i.e. 5 mg in the evening and fir me that the muscle spasms are under control. Nice to chat. Helen 😊

   

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avatar
Yank34
on 01/11/2019

Prior to the 1st of April 2013, I had been totally unaware/in denial(?), although a retired Registered Gener, that I'd had MS since the Spring of 1978.  Throughout the years, had attributed my multitudinous but remitting symptoms to literally "everything under the sun" EXCEPT MS!  The very 1st time I took a 10mg tablet of baclofen (way back, probably sometime in 2013 (perhaps early 2014?), I was totally amazed...…..felt the way I did before my MS changed/progressed(?) very dramatically to SPMS!  Unfortunately this very quickly changed and in accordance with directions from my MS Nurse and Patient Information Leaflet, needed to begin to increase the dosage to alleviate my growing problematic spasticity.  Although I believed this increase was gradually facilitated, in hindsight probably conducted this far too quickly?  Rather than better controlling my spasticity, it increased to the point that my muscle spasms became uncontrollable, almost constantly experiencing "tics and jerks" resembling someone with cerebral palsy +/or Tourette's Syndrome (without the verbal "tics"/shouting words").  Because of this extremely adverse reaction, needed to stop the baclofen for quite some months, replacing it with diazepam (2mg x 4-6 tablets).  It seemed it took a long time, uncertain as to how long this actually was before I took the "giant leap", after consulting my MS Nurse, to SLOWLY replace/re-introduce the baclofen.  Happily my spasticity became more effectively controlled, by the baclofen, only taking 2mg diazepam before going to bed but can never be sure if the change in medication(s) were responsible for this improvement or if my always unpredictable MS had "calmed down"?  I do experience a dry mouth and  another baclofen user has reported muscle weakness from taking it but personally, agree with my very experienced MS Nurse "baclofen is the drug of choice" for MS spasticity.

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avatar
Yank34
on 01/11/2019

Hi larraine11.  Just saw your comment/post re: baclofen (for spasticity) and must say I soooo loved your last sentence about NOT falling over ……….sooooo made me laugh!!!!!!!  I've been on baclofen, probably since about 2013 and my MS Nurse did say it was the "drug of choice" for MS spasticity (have probably had MS since 1978).  At the moment, only taking 10mg 2x a day (1st thing in morning and last thing as night) but have been known to take 1-2 "additional" tablets if/when spasticity is particularly problematic.  Certainly agree re: the dry mouth side-effect but hopefully have NOT experienced muscle weakness but perhaps because I try to be as active as possible to prevent this?  May also help with sleeping - but get sooooooo tired do fall asleep quite easily even though because baclofen only is effective for about 4hrs, spasticity, most nights, does wake me up but because I am always soooo tired, just try to re-position although my MS Nurse (who is a gem!) suggested when this happens to take another baclofen NOT doing this as personally feel this would more greatly interfere with my sleep.  Hope you are ok and "lovely to see your comment"! x

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avatar
larraine11
on 06/06/2019

Swings and roundabouts really! Definitely helps with high tone,eases muscles spasms,I have neurological problems it does help and improves sleeping.Problems..dry mouth and excessive weakness,so do not fall over while you are taking it,as you will not be strong enough to get back up!

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Members using this Baclofen

Conditions related to this medication

Fact sheet

Spasticity

See the fact sheet
Fact sheet

Syringomyelia

See the fact sheet
See the fact sheet