Letrozole (letrozole): Reviews and patient testimonials

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Medication indications

Letrozole 2.5 mg Film-coated tablets

Adjuvant treatment of postmenopausal women with hormone receptor positive invasive early breast cancer.

Extended adjuvant treatment of hormone-dependent-invasive breast cancer in postmenopausal women who have received prior standard adjuvant tamoxifen therapy for 5 years.

First-line treatment in postmenopausal women with hormone-dependent advanced breast cancer.

Advanced breast cancer after relapse or disease progression, in women with natural or artificially induced postmenopausal endocrine status, who have previously been treated with anti-oestrogens.

Neo-adjuvant treatment of postmenopausal women with hormone receptor positive, HER-2 negative breast cancer where chemotherapy is not suitable and immediate surgery not indicated.

Efficacy has not been demonstrated in patients with hormone receptor negative breast cancer.

Letrozole 2.5 mg film-coated tablets

- Adjuvant treatment of postmenopausal women with hormone receptor positive invasive early breast cancer.

- Extended adjuvant treatment of hormone-dependent invasive breast cancer in postmenopausal women who have received prior standard adjuvant tamoxifen therapy for 5 years.

- First-line treatment in postmenopausal women with hormone-dependent advanced breast cancer.

- Advanced breast cancer after relapse or disease progression, in women with natural or artificially induced postmenopausal endocrine status, who have previously been treated with anti-oestrogens.

- Neo-adjuvant treatment of postmenopausal women with hormone receptor positive, HER-2 negative breast cancer where chemotherapy is not suitable and immediate surgery not indicated.

Efficacy has not been demonstrated in patients with hormone receptor negative breast cancer.

Letrozole 2.5mg film-coated tablets

• Adjuvant treatment of postmenopausal women with hormone receptor positive invasive early breast cancer.

• Extended adjuvant treatment of hormone-dependent-invasive breast cancer in postmenopausal women who have received prior standard adjuvant tamoxifen therapy for 5 years.

• First-line treatment in postmenopausal women with hormone-dependent advanced breast cancer.

• Advanced breast cancer in women with natural or artificially induced postmenopausal endocrine status after relapse or disease progression, who have previously been treated with anti-oestrogens.

• Neo-adjuvant treatment of postmenopausal women with hormone receptor positive, HER-2 negative breast cancer where chemotherapy is not suitable and immediate surgery not indicated.

Efficacy has not been demonstrated in patients with hormone-receptor negative breast cancer.

Letrozole 2.5mg film-coated Tablets.

• Adjuvant treatment of postmenopausal women with hormone receptor positive invasive early breast cancer.

• Extended adjuvant treatment of hormone-dependent invasive breast cancer in postmenopausal women who have received prior standard adjuvant tamoxifen therapy for 5 years.

• First-line treatment in postmenopausal women with hormone-dependent advanced breast cancer.

• Advanced breast cancer after relapse or disease progression, in women with natural or artificially induced postmenopausal endocrine status, who have previously been treated with anti-oestrogens.

• Neo-adjuvant treatment of postmenopausal women with hormone receptor positive, HER-2 negative breast cancer where chemotherapy is not suitable and immediate surgery not indicated.

Efficacy has not been demonstrated in patients with hormone receptor negative breast cancer.


Route of administration: Oral
Molecule: letrozole

Patients' opinions on Letrozole

In brief

General satisfaction level: 4.67/10 Learn more

Treatment's effectiveness: 7.33/10 Learn more

Ease of use: 9.50/10 Learn more

Adherence to prescription: 10.00/10 Learn more

Detected side effects: 5.67/10 Learn more

Improvement in the quality of life: 4.67/10 Learn more

1 = Not at all satisfied
10 = Extremely satisfied

1 = Not at all satisfied
10 = Extremely satisfied

1 = Not at all satisfied
10 = Extremely satisfied

1 = Never
10 = Always

1 = Not at all important
10 = Extremely important

1 = Not at all satisfied
10 = Extremely satisfied

Tips and advice of the community


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Susie39
on 07/10/2020

Changed my brand to Femara. Experiencing much less pain in my hands

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Tigger.co.uk
on 15/05/2020

Hi there I'm on anastrazole now had to come off of letrazole  because my hot flushes was really bad and I was in a lot of pain I'm still get a lot of pain and the  hot flushes so I'm just carrying on with them as it must be helping my cancer so I cant keep swapping and changing as I take so much other medication ,its a wonder I dont rattle as I walk lol ,now I have a chest infection and having to start on my stand by antibiotics and steroids, but feeling very drained and my arms are really aching on my lymphoedema and my osteoporosis arthritis is causing pain to. Tigger 

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Heather-Honey
on 09/05/2020

I have an underactive thyroid so need to take levothyroxine daily. As this is also hormone based I didn't want to take at the same time as I have read it might interfere so take letrozole at night and if I can sleep I don't feel the leg pains as much.

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Susie39
on 05/11/2019

I have been on Letrozole for four months. No real side effects so far . See how it goes. 

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Sandie7
on 05/11/2019

Tried all three arimidex exemastane and now letroxole been on the latter for 7 years ruined my quality of life side effects are numerous.

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Tigger.co.uk
on 06/09/2019

Had to come off of letrazole as I was in a lot of pain with my osteoporosis also hot flushes was bad to 

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Tigger.co.uk
on 06/06/2019

Hi sandie I was like you I had these symptoms and my oncologists changed my prescription to something else as I was getting really bad hot flushes ,joint pain, and numbness in my hand so she changed my meds to anastrozole but still get my flushes and now suffer with brittle bones 

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Sandie7
on 21/04/2019

I have been taking these poisons now ie arimidex exemerstane and letrozole since 2010 and they'e ruined my life I'm in constant joint pain can' t sleep hands keep going numb in the night I'm more or less housebound and was always a very active person

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Members using this Letrozole

Conditions related to this medication

Fact sheet

Breast cancer

See the fact sheet