Zoladex (goserelin): Reviews and patient testimonials

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Medication indications

Zoladex 3.6mg Implant

(i) Treatment of prostate cancer in the following settings (see also section 5.1):

• In the treatment of metastatic prostate cancer where Zoladex has demonstrated comparable survival benefits to surgical castrations

• In the treatment of locally advanced prostate cancer, as an alternative to surgical castration where Zoladex has demonstrated comparable survival benefits to an anti-androgen

• As adjuvant treatment to radiotherapy in patients with high-risk localised or locally advanced prostate cancer where Zoladex has demonstrated improved disease-free survival and overall survival

• As neo-adjuvant treatment prior to radiotherapy in patients with high-risk localised or locally advanced prostate cancer where Zoladex has demonstrated improved disease-free survival

• As adjuvant treatment to radical prostatectomy in patients with locally advanced prostate cancer at high risk of disease progression where Zoladex has demonstrated improved disease-free survival

(ii) Advanced breast cancer in pre and perimenopausal women suitable for hormonal manipulation.

(iii) Zoladex 3.6 mg is indicated as an alternative to chemotherapy in the standard of care for pre/perimenopausal women with oestrogen receptor (ER) positive early breast cancer.

(iv) Endometriosis: In the management of endometriosis, Zoladex alleviates symptoms, including pain, and reduces the size and number of endometrial lesions.

(v) Endometrial thinning: Zoladex is indicated for the prethinning of the uterine endometrium prior to endometrial ablation or resection.

(vi) Uterine fibroids: In conjunction with iron therapy in the haematological improvement of anaemic patients with fibroids prior to surgery.

(vii) Assisted reproduction: Pituitary downregulation in preparation for superovulation.

Zoladex LA 10.8mg

Zoladex is indicated (see also section 5.1):

• In the treatment of metastatic prostate cancer where Zoladex has demonstrated comparable survival benefits to surgical castrations

• In the treatment of locally advanced prostate cancer, as an alternative to surgical castration where Zoladex has demonstrated comparable survival benefits to an anti-androgen

• As adjuvant treatment to radiotherapy in patients with high-risk localised or locally advanced prostate cancer where Zoladex has demonstrated improved disease-free survival and overall survival

• As neo-adjuvant treatment prior to radiotherapy in patients with high-risk localised or locally advanced prostate cancer where Zoladex has demonstrated improved disease-free survival

• As adjuvant treatment to radical prostatectomy in patients with locally advanced prostate cancer at high risk of disease progression where Zoladex has demonstrated improved disease-free survival
Molecule: goserelin

Patients' opinions on Zoladex

In brief

General satisfaction level: 5.00/10 Learn more

Treatment's effectiveness: 9.00/10 Learn more

Ease of use: 7.50/10 Learn more

Adherence to prescription: 9.00/10 Learn more

Detected side effects: 6.50/10 Learn more

Improvement in the quality of life: 7.00/10 Learn more

1 = Not at all satisfied
10 = Extremely satisfied

1 = Not at all satisfied
10 = Extremely satisfied

1 = Not at all satisfied
10 = Extremely satisfied

1 = Never
10 = Always

1 = Not at all important
10 = Extremely important

1 = Not at all satisfied
10 = Extremely satisfied

Tips and advice of the community


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maddoglady
on 30/06/2018

Horrible stuff, hated having to go to GP for sub cut injections. Caused horrible menopausal symptoms. Effective though.


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Haworthian
on 09/03/2021

I've had two successive implants and the flushes have been intense, particularly in bed at night, and often quite painful. Still, my specialist is giving me a 'holiday' from it for six months so I can't complain too much.

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Haworthian
on 09/03/2021

Be fully informed about the side effects attached to Zoladex. 

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Haworthian
on 05/01/2021

The side-effects - as previously noted there are awful 'menopausal-style' symptoms and total loss of both libido and erectile function - are tough to deal with but it reduced my rising PSA from 7.3 to 0.034. I'm 18 years post radical prostatectomy and nine years post-radiotherapy with a Gleason Scale cancer of 7 (4+3). So Zoladex is not great but it's far, far better than the alternative!

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Members using this Zoladex

Conditions related to this medication

Fact sheet

Breast cancer

See the fact sheet
Fact sheet

Prostate cancer

See the fact sheet
Fact sheet

Endometriosis

See the fact sheet