'World first' trial in Cardiff for new treatment for Type 1 diabetes
Published 24 Sep 2018
A 'ground-breaking' clinical trial has been launched in Cardiff to help prevent and manage Type 1 diabetes.
The Clinical Research Facility at Cardiff and Vale University Health Board has dosed the first patient in the world with the new investigational drug. It aims to help the regrowth of insulin making ‘beta’ cells of the pancreas, which are lost in patients living with the disease.
Type 1 diabetes is a serious, lifelong condition where blood glucose levels are too high because the body cannot make a hormone called insulin. Those with Type 1 diabetes are dependent on insulin but if this clinical trial works, the regrowth - or regeneration - of beta cells may mean those with Type 1 diabetes becoming far less dependent on insulin injections.
So far, the drug appears to have had no major side-effects, but it is too early to say if it has been effective. The Cardiff team is hoping to attract up to eight adult volunteers to take part in the clinical trial who have had diabetes for more than two years.
"Despite everything achieved in diabetes care, advances in prevention haven’t really occurred. More insulin-producing beta cells are needed for those with this form of diabetes and it is estimated that 90% of patients with Type 1 diabetes have less", added Dr Mohammad Alhadj Ali.
Would you be interesting in trialing this medication?
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@JaneHewitt Hello Jane,
It is great that you are interested! I don't have the contact details for the Cardiff department but if you have a look aorund online, you would probably be able to find it. I don't want to put you in the wrong direction by providing you with contact details that could prove wrong.
Please come back and tell us if it works out :)
I would love to take part in this being diabetic since 18 months old now 37 millerkaren781@gmail.com
@millerkaren Hello,
As I mentioned above, I don't have the contact details for the Cardiff department but if you have a look around online, you would probably be able to find it. I don't want to put you in the wrong direction by providing you with contact details that could prove wrong but it does seem like a really great study!
Please come back and tell us if it works out :)
I would be very interested in taking part in this trial. I was diagnosed with Type 1 just before my 14th birthday and have now lived with the condition for more than 44 years. The management of it has changed dramatically for the better during that period of time, including the range of insulin, pen delivery, pumps and, thank goodness for DAFNE! However, I believe that research such as yours in Cardiff could be life-changing.
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