Calcium Folinate (calcium folinate): Reviews and patient testimonials

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Medication indications

Calcium Folinate 10 mg/ml Injection

Calcium folinate is indicated

a) to diminish the toxicity and counteract the action of folic acid antagonists such as methotrexate in cytotoxic therapy and overdose in adults and children. In cytotoxic therapy, this procedure is commonly known as “Calcium Folinate Rescue”;

b) in combination with 5-fluorouracil in cytotoxic therapy.

Calcium Folinate 10mg/ml Solution for injection or infusion

Calcium folinate is indicated:

- to diminish the toxicity and counteract the action of folic acid antagonists such as methotrexate in cytotoxic therapy and overdose in adults and children. In cytotoxic therapy, this procedure is commonly known as “Calcium Folinate Rescue”;

- in combination with 5-fluorouracil in cytotoxic therapy.

Calcium Folinate 15 mg Tablets

Calcium Folinate is indicated in:

1. Neutralising the immediate toxic effects of folic acid antagonists, e.g. Methotrexate.

2. Calcium Folinate Rescue - a treatment technique using Calcium Folinate in conjunction with folic acid antagonists, e.g. methotrexate, to minimise systemic toxicity.

3. The treatment of megaloblastic anaemias due to sprue, nutritional deficiency, pregnancy, infancy, liver disease and malabsoption syndrome.

Calcium Folinate 15mg Tablets

Leucovorin (folinic acid) is the formyl derivative of tetrahydrofolic acid which is a metabolite and active form of folic acid.

Calcium Folinate is indicated in:

a) Neutralising the immediate toxic effects of folic acid antagonists, e.g. Methotrexate.

b) Calcium Folinate Rescue - a treatment technique using Calcium Folinate in conjunction with folic acid antagonists, e.g. methotrexate, to minimise systemic toxicity.

c) The treatment of megaloblastic anaemias due to sprue, nutritional deficiency, pregnancy, infancy, liver disease and malabsorption syndrome.

Calcium Folinate 3 mg/ml Injection

Calcium folinate is indicated

a) to diminish the toxicity and counteract the action of folic acid antagonists such as methotrexate in cytotoxic therapy and overdose in adults and children. In cytotoxic therapy, this procedure is commonly known as “Calcium Folinate Rescue”;

Calcium Folinate 7.5 mg/mL Injection

Calcium folinate is indicated

a) to diminish the toxicity and counteract the action of folic acid antagonists such as methotrexate in cytotoxic therapy and overdose in adults and children. In cytotoxic therapy, this procedure is commonly known as “Calcium Folinate Rescue”;

b) in combination with 5-fluorouracil in cytotoxic therapy.


Route of administration: Injectable, Oral
Molecule: calcium folinate

Patients' opinions on Calcium Folinate

In brief

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1 = Not at all satisfied
10 = Extremely satisfied

1 = Not at all satisfied
10 = Extremely satisfied

1 = Not at all satisfied
10 = Extremely satisfied

1 = Never
10 = Always

1 = Not at all important
10 = Extremely important

1 = Not at all satisfied
10 = Extremely satisfied

Tips and advice of the community

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Conditions related to this medication

Fact sheet

Celiac disease

See the fact sheet