«
»

Top

'World first' trial in Cardiff for new treatment for Type 1 diabetes

Published 24 Sep 2018

'World first' trial in Cardiff for new treatment for Type 1 diabetes

A 'ground-breaking' clinical trial has been launched in Cardiff to help prevent and manage Type 1 diabetes.

DT1

The Clinical Research Facility at Cardiff and Vale University Health Board has dosed the first patient in the world with the new investigational drug. It aims to help the regrowth of insulin making ‘beta’ cells of the pancreas, which are lost in patients living with the disease.

Type 1 diabetes is a serious, lifelong condition where blood glucose levels are too high because the body cannot make a hormone called insulin. Those with Type 1 diabetes are dependent on insulin but if this clinical trial works, the regrowth - or regeneration - of beta cells may mean those with Type 1 diabetes becoming far less dependent on insulin injections.

So far, the drug appears to have had no major side-effects, but it is too early to say if it has been effective. The Cardiff team is hoping to attract up to eight adult volunteers to take part in the clinical trial who have had diabetes for more than two years.

"Despite everything achieved in diabetes care, advances in prevention haven’t really occurred. More insulin-producing beta cells are needed for those with this form of diabetes and it is estimated that 90% of patients with Type 1 diabetes have less", added Dr Mohammad Alhadj Ali.

Would you be interesting in trialing this medication?

Itv.com

14 comments


lesmal • Ambassador
on 24/09/2018

Wishing you every success with this study and may this new drug help with the regrowth of insulin! 

This would save so much time and effort with those who have to inject themselves with insulin daily... It would be so much easier to 'pop a pill'!

Hoping eight adult volunteers can be found soon to take part in this great clinical trial! 


JosephineO • Community manager
on 25/09/2018

@lesmal Yes, it would be great to change the method that diabetes sufferers can receive their insulin and make it easier for them. 

It will be interesting to see how this study advances. 


JaneHewitt
on 27/09/2018

I would be very interested in taking part in this trial, if anyone from the team can contact me, my email address is janehewitt50@sky.com


Mark_O
on 27/09/2018

This is very exciting. Hope eight volunteers have been found, if not?  Young 48 year old (me) would definitely be willing to move to Cardiff to get involved. Good luck 


John Heathershaw
on 27/09/2018

I would be very interested in having a trial of this treatment. I have been a Type 1 diabetic for 47 years, so any alternative treatment would be exciting.

You will also like

Diabetes: Discrimination, Professional Life, Plan Ahead... What do patients say?

Diabetes (Type 1)

Diabetes: Discrimination, Professional Life, Plan Ahead... What do patients say?

Read the article
Diabetes: Switching to common drugs raises risk of complications

Diabetes insipidus

Diabetes: Switching to common drugs raises risk of complications

Read the article
Specialists Call for Gastric Surgery to Be Standard Diabetes Treatment

Diabetes (Type 1)

Specialists Call for Gastric Surgery to Be Standard Diabetes Treatment

Read the article
See the testimonial

Fact sheet