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Posted on 11/30/17 2:07 PM
Small amounts of artificial vanilla extract, also known as vanillin, are in a wide range of products, from baked goods to perfumes. But vanillin's versatility doesn't stop there. In a recent mouse study reported in ACS' Journal of Agricultural and Food Chemistry, researchers report that this compound could also prevent or reduce psoriatic skin inflammation.
Psoriasis is an inflammatory skin disorder that affects about 125 million people worldwide, resulting in scaly red plaques that typically show up on the elbows, knees or scalp. Immune system proteins called interleukins (IL) 17 and 23 are known to be key players in the development of the condition. Interestingly, vanillin can have effects on different interleukins that are involved in other inflammatory conditions and diseases. So, Chien-Yun Hsiang and Tin-Yun Ho wanted to see if treatment with vanillin could prevent psoriatic symptoms.
The researchers induced psoriatic skin inflammation on groups of mice by putting a compound called imiquimod on their skin. In addition, the mice were orally given daily doses (0, 1, 5, 10, 50 or 100 milligrams/kilograms of body weight) of vanillin for seven days. Mice treated with 50- or 100-milligram/kilograms of body weight doses had reduced psoriatic symptoms compared to those receiving smaller or no doses of vanillin. In all mice treated with vanillin, IL-17 and IL-23 protein levels were decreased. The researchers say that vanillin was an effective compound against psoriatic skin inflammation in this animal model.
Beginning of the discussion - 12/11/17Preventing psoriasis with vanillia extract https://www.carenity.co.uk/forum/psoriasis/my-library-psoriasis/preventing-psoriasis-with-vanillia-extract-2085
Posted on 12/11/17 1:45 PM
I am in Sussex and I have an excellent Consultant who understands everything for Psoriasis. I have numerous problems some connected to Psoriasis and others that are not. I have Ehlers-Danlos a very rare type from my father, I have Crohn's too, my mother had colitis. I have Spina Bifida Occulta frommy mother and a tiny cyst both congenital.
Posted on 1/8/18 2:53 PM
How much vanilla extract would I need to take daily to help my psoriasis as it is very red at present?
Posted on 1/9/18 10:14 AM
Hi @Hidden username ,
I am sorry but cannot tell you this, because I am not a medical professional.
In any case, for now, the vanilla extract has only been proved beneficial to mice, and there is no evidence yet as to its effect on humans. This article was shared for information purpose only.
If you are having a flare up at the moment, I suggest you talk to your consultant to see what you can do to ease the symptoms. Only a doctor can advise you on treatments and their dosage.
Hope it will get better soon!
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